A. Bleasby: search on Z-Library

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1

Species differences in drug transporters and implications for translating preclinical findings to humans

Chu, Xiaoyan, Bleasby, Kelly, Evers, Raymond

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2013

Language:

english

File:

PDF, 443 KB

english, 2013

2

DNAPlotter: circular and linear interactive genome visualization

Carver, T., Thomson, N., Bleasby, A., Berriman, M., Parkhill, J.

Journal:

Year:

2009

Language:

english

File:

PDF, 319 KB

english, 2009

3

The Complexities of Interpreting Reversible Elevated Serum Creatinine Levels in Drug Development: Does a Correlation with Inhibition of Renal Transporters Exist?

Chu, X., Bleasby, K., Chan, G. H., Nunes, I., Evers, R.

Journal:

Drug Metabolism and Disposition

Year:

2016

Language:

english

File:

PDF, 4.52 MB

english, 2016

4

A computer system for analysis of chromatographic data

R.J. Marshall, A.J. Bleasby, R. Turner, E.H. Cooper

Journal:

Chemometrics and Intelligent Laboratory Systems

Year:

1987

Language:

english

File:

PDF, 829 KB

english, 1987

5

EMBOSS: The European Molecular Biology Open Software Suite

Peter Rice, Ian Longden, Alan Bleasby

Journal:

Trends in Genetics

Year:

2000

Language:

english

File:

PDF, 150 KB

english, 2000

6

The Bioinformatics Resource

Jon C Ison, Sinead B O’Leary, Alan J Bleasby, David Moss

Journal:

Trends in Biochemical Sciences

Year:

2000

Language:

english

File:

PDF, 39 KB

english, 2000

7

A cluster randomised controlled trial of a web based decision aid to support parents’ decisions about their child's Measles Mumps and Rubella (MMR) vaccination

Shourie, S., Jackson, C., Cheater, F.M., Bekker, H.L., Edlin, R., Tubeuf, S., Harrison, W., McAleese, E., Schweiger, M., Bleasby, B., Hammond, L.

Journal:

Year:

2013

Language:

english

File:

PDF, 652 KB

english, 2013

8

Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: A resource for investigations into drug disposition

Bleasby, K., Castle, J. C., Roberts, C. J., Cheng, C., Bailey, W. J., Sina, J. F., Kulkarni, A. V., Hafey, M. J., Evers, R., Johnson, J. M., Ulrich, R. G., Slatter, J. G.

Journal:

Year:

2006

Language:

english

File:

PDF, 645 KB

english, 2006

9

Transporters affecting biochemical test results: Creatinine-drug interactions

Chu, X, Bleasby, K, Chan, GH, Nunes, I, Evers, R

Journal:

Clinical Pharmacology & Therapeutics

Year:

2016

Language:

english

File:

PDF, 191 KB

english, 2016

10

Key residues approach to the definition of protein families and analysis of sparse family signatures

Jon C. Ison, Matthew J. Blades, Alan J. Bleasby, Stephen C. Daniel, J. Howard Parish, John B.C. Findlay

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2000

Language:

english

File:

PDF, 564 KB

english, 2000

11

ChemInform Abstract: The PRINTS Database of Protein Fingerprints: A Novel Information Resource for Computational Molecular Biology

T. K. ATTWOOD, H. AVISON, M. E. BECK, M. BEWLEY, A. J. BLEASBY, F. BREWSTER, P. COOPER, K. DEGTYARENKO, A. J. GEDDES, D. R. FLOWER, M. P. KELLY, S. LOTT, K. M. MEASURES, D. J. PARRY-SMITH, D. N. PERKI

Journal:

Year:

1997

File:

PDF, 27 KB

1997

12

Exported proteins of Neurospora crassa: 1-glucoamylase

Siok Im Koh-Luar, J.H. Parish, A.J. Bleasby, D.J.C. Pappin, K. Ainley, F.-E. Johansen, M.J. McPherson, A. Radfors

Journal:

Enzyme and Microbial Technology

Year:

1989

Language:

english

File:

PDF, 333 KB

english, 1989

13

Two cyclic AMP-regulated genes from Dictyostelium discoideum encode homologous proteins

D. P. Ramji, A. J. Richards, P. Jagger, A. Bleasby, B. D. Hames

Journal:

Molecular Microbiology

Year:

1990

Language:

english

File:

PDF, 2.64 MB

english, 1990

14

Characterization of MPP+ secretion across human intestinal Caco-2 cell monolayers: role of P-glycoprotein and a novel Na+-dependent organic cation transport mechanism

Kelly Bleasby, Seema Chauhan, Colin D A Brown

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 206 KB

english, 2000

15

The organic cation transporter OCT2 mediates the uptake of β-adrenoceptor antagonists across the apical membrane of renal LLC-PK1 cell monolayers

Adam J Dudley, Kelly Bleasby, Colin D A Brown

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 196 KB

english, 2000

16

QSAR Prediction of Passive Permeability in the LLC-PK1 Cell Line: Trends in Molecular Properties and Cross-Prediction of Caco-2 Permeabilities

Edward C. Sherer, Andreas Verras, Maria Madeira, William K. Hagmann, Robert P. Sheridan, Drew Roberts, Kelly Bleasby, Wendy D. Cornell

Journal:

Molecular Informatics

Year:

2012

Language:

english

File:

PDF, 885 KB

english, 2012

17

Cell interactions during the fusionin vitroofDrosophilaeye-antennal imaginal discs

Martin J. Milner, Alison J. Bleasby, Andrew Pyott

Journal:

Development Genes and Evolution

Year:

1984

Language:

english

File:

PDF, 5.05 MB

english, 1984

18

The role of the peripodial membrane in the morphogenesis of the eye-antennal disc ofDrosophila melanogaster

Martin John Milner, Alison Jane Bleasby, Andrew Pyott

Journal:

Development Genes and Evolution

Year:

1983

Language:

english

File:

PDF, 3.22 MB

english, 1983

19

The role of the peripodial membrane of leg and wing imaginal discs ofDrosophila melanogasterduring evagination and differentiation in vitro

Martin J. Milner, Alison J. Bleasby, Susan L. Kelly

Journal:

Development Genes and Evolution

Year:

1984

Language:

english

File:

PDF, 2.87 MB

english, 1984

20

Rapid identification of proteins by peptide-mass fingerprinting

D.J.C. Pappin, P. Hojrup, A.J. Bleasby

Journal:

Current Biology

Year:

1993

Language:

english

File:

PDF, 940 KB

english, 1993

21

Impact of passive permeability and gut efflux transport on the oral bioavailability of novel series of piperidine-based renin inhibitors in rodents

Jean-François Lévesque, Kelly Bleasby, Amandine Chefson, Austin Chen, Daniel Dubé, Yves Ducharme, Pierre-André Fournier, Sébastien Gagné, Michel Gallant, Erich Grimm, Michael Hafey, Yongxin Han, Rober

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 482 KB

english, 2011

22

Nicotinic acids: Liver-targeted SCD inhibitors with preclinical anti-diabetic efficacy

David A. Powell, W. Cameron Black, Kelly Bleasby, Chi-Chung Chan, Denis Deschenes, Marc Gagnon, Rob Gordon, Jocelyne Guay, Sebastien Guiral, Michael J. Hafey, Zheng Huang, Elise Isabel, Yves Leblanc,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.18 MB

english, 2011

23

The discovery of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitors

Thomas H. Graham, Hong C. Shen, Wensheng Liu, Yusheng Xiong, Andreas Verras, Kelly Bleasby, Urmi R. Bhatt, Renee M. Chabin, Dunlu Chen, Qing Chen, Margarita Garcia-Calvo, Wayne M. Geissler, Huaibing H

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.97 MB

english, 2012

24

A new class of prolylcarboxypeptidase inhibitors, Part 2: The aminocyclopentanes

Thomas H. Graham, Wensheng Liu, Andreas Verras, Mikhail Reibarkh, Kelly Bleasby, Urmi R. Bhatt, Qing Chen, Margarita Garcia-Calvo, Wayne M. Geissler, Judith N. Gorski, Huaibing He, Michael E. Lassman,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.82 MB

english, 2012

25

A new class of prolylcarboxypeptidase inhibitors, Part 1: Discovery and evaluation

Thomas H. Graham, Wensheng Liu, Andreas Verras, Iyassu K. Sebhat, Yusheng Xiong, Kelly Bleasby, Urmi R. Bhatt, Qing Chen, Margarita Garcia-Calvo, Wayne M. Geissler, Judith N. Gorski, Huaibing He, Mich

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 3.12 MB

english, 2012

26

Microheterogeneity of α1-acid glycoprotein: Lack of discrimination between benign and malignant inflammatory disease of the lung

Alan J Bleasby, Judy C Knowles, Nigel J Cooke

Journal:

Clinica Chimica Acta

Year:

1985

Language:

english

File:

PDF, 900 KB

english, 1985

27

Rosuvastatin is a high affinity substrate of hepatic organic anion transporter OATP-C

Brown, C.D.A., Windass, A., Bleasby, K., Lauffart, B.

Journal:

Atherosclerosis Supplements

Year:

2001

Language:

english

File:

PDF, 174 KB

english, 2001

28

Development of a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor (MK-8245) to Establish a Therapeutic Window for the Treatment of Diabetes and Dyslipidemia

Oballa, Renata M., Belair, Liette, Black, W. Cameron, Bleasby, Kelly, Chan, Chi Chung, Desroches, Carole, Du, Xiaobing, Gordon, Robert, Guay, Jocelyne, Guiral, Sebastien, Hafey, Michael J., Hamelin, E

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.27 MB

english, 2011

29

Databases for chemistry and molecular biology

Bleasby, A.J., Curwen, L.S., McMeeking, R.F., Sherman, H.J.

Journal:

Trends in Food Science & Technology

Year:

1991

Language:

english

File:

PDF, 371 KB

english, 1991

30

The BIOSCI newsgroup-computer networks changing biology

Bleasby, Alan, Griffiths, Paul, Hines, David, Marshall, Steve, Staniford, Lisa, Hoover, Kenton, Kristofferson, David

Journal:

Trends in Biochemical Sciences

Year:

1993

Language:

english

File:

PDF, 199 KB

english, 1993

31

The design of Jemboss: a graphical user interface to EMBOSS

Carver, T., Bleasby, A.

Journal:

Year:

2003

Language:

english

File:

PDF, 105 KB

english, 2003

32

Singular over-representation of an octameric palindrome, HIP1, in DNA from many cyanobacteria

Robinson, Nigel J., Robinson, Pamela J., Gupta, Amit, Bleasby, Alan J., Whitton, Brian A., Morby, Andrew P.

Journal:

Nucleic Acids Research

Year:

1995

Language:

english

File:

PDF, 1.69 MB

english, 1995

33

The PRINTS Database of Protein Fingerprints: A Novel Information Resource for Computational Molecular Biology

Attwood, T.K., Avison, H., Beck, M.E., Bewley, M., Bleasby, A.J., Brewster, F., Cooper, P., Degtyarenko, K., Geddes, A.J., Flower, D.R., Kelly, M.P., Lott, S., Measures, K.M., Parry-Smith, D.J., Perki

Journal:

Journal of Chemical Information and Modeling

Year:

1997

Language:

english

File:

PDF, 238 KB

english, 1997

34

[IEEE 2007 Latin American Network Operations and Management Symposium - Petropolis, Rio de Janeiro, Brazil (2007.09.10-2007.09.12)] 2007 Latin American Network Operations and Management Symposium - A Test-oriented Architecture for Network Fault Management

Salles, Ronaldo, Cecilio, Edmundo, Cardoso, Sergio, Correia, Adolfo, Bleasby, Fabio

Year:

2007

Language:

english

File:

PDF, 2.32 MB

english, 2007

35

The metabolism and disposition of a potent inhibitor of hepatitis C virus NS3/4A protease

Monteagudo, E., Fonsi, M., Chu, X., Bleasby, K., Evers, R., Pucci, V., Orsale, M.V., Cianetti, S., Ferrara, M., Harper, S., Laufer, R., Rowley, M., Summa, V.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.15 MB

english, 2010

36

CLUSTAL V: improved software for multiple sequence alignment

Higgins, Desmond G., Bleasby, Alan J., Fuchs, Rainer

Journal:

Year:

1992

Language:

english

File:

PDF, 263 KB

english, 1992

37

[IEEE 2006 Second IEEE International Conference on e-Science and Grid Computing (e-Science'06) - Amsterdam, The Netherlands (2006.12.4-2006.12.4)] 2006 Second IEEE International Conference on e-Science and Grid Computing (e-Science'06) - EMBRACE: Bioinformatics Data and Analysis Tool Services for e-Science

Rice, Peter, Bleasby, Alan, Haider, Syed, Ison, Jon, McGlinchey, Shaun, Uludag, Mahmut

Year:

2006

Language:

english

File:

PDF, 158 KB

english, 2006

38

Construction of validated, non-redundant composite protein sequence databases

Bleasby, Alan J., Wootton, John C.

Journal:

Protein Engineering Design and Selection

Year:

1990

Language:

english

File:

PDF, 3.79 MB

english, 1990

39

Transport of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin by Human Organic Anion Transporter 3, Organic Anion Transporting Polypeptide 4C1, and Multidrug Resistance P-glycoprotein

Chu, X.-Y., Bleasby, K., Yabut, J., Cai, X., Chan, G. H., Hafey, M. J., Xu, S., Bergman, A. J., Braun, M. P., Dean, D. C., Evers, R.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2007

Language:

english

File:

PDF, 513 KB

english, 2007

40

Novel developments with the PRINTS protein fingerprint database

Attwood, T. K., Beck, M. E., Bleasby, A. J., Degtyarenko, K., Michie, A. D., Parry-Smith, D. J.

Journal:

Nucleic Acids Research

Year:

1997

Language:

english

File:

PDF, 236 KB

english, 1997

41

Editorial: Stable funding for open source software?

Journal:

Briefings in Bioinformatics

Year:

2004

Language:

english

File:

PDF, 38 KB

english, 2004

42

Madin-Darby Canine Kidney II Cells: A Pharmacologically Validated System for NPC1L1-Mediated Cholesterol Uptake

Weinglass, A. B., Kohler, M. G., Nketiah, E. O., Liu, J., Schmalhofer, W., Thomas, A., Williams, B., Beers, L., Smith, L., Hafey, M., Bleasby, K., Leone, J., Tang, Y. S., Braun, M., Ujjainwalla, F., M

Journal:

Molecular Pharmacology

Year:

2008

Language:

english

File:

PDF, 627 KB

english, 2008

43

The Bioinformatics Template Library--generic components for biocomputing

Pitt, W. R., Williams, M. A., Steven, M., Sweeney, B., Bleasby, A. J., Moss, D. S.

Journal:

Year:

2001

Language:

english

File:

PDF, 232 KB

english, 2001

44

Functional Consequences of Single Nucleotide Polymorphisms in the Human Organic Anion Transporter hOAT1 (SLC22A6)

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2005

Language:

english

File:

PDF, 424 KB

english, 2005

45

Importance of mechanistic drug metabolism studies in support of drug discovery: A case study with an N -sulfonylated dipeptide VLA-4 antagonist in rats

Tang, W., Stearns, R. A., Chen, Q., Bleasby, K., Teffera, Y., Colletti, A., Hafey, M., Evers, R., Dean, D. C., Magriotis, P. A., Lanza, T. J., Lin, L. S., Hagmann, W. K., Baillie, T. A.

Journal:

Year:

2008

Language:

english

File:

PDF, 152 KB

english, 2008

46

Electronic communications and the new biology

Bleasby, Alan, Griffiths, Paul, Harper, Robert, Hines, David, Hoover, Kenton, Kristofferson, David, Marshall, Steve, O'Reilly, Niall, Sundvall, Mats

Journal:

Nucleic Acids Research

Year:

1992

Language:

english

File:

PDF, 134 KB

english, 1992

47

The flounder organic anion transporter fOat has sequence, function, and substrate specificity similarity to both mammalian Oat1 and Oat3

Aslamkhan, A. G., Thompson, D. M., Perry, J. L., Bleasby, K., Wolff, N. A., Barros, S., Miller, D. S., Pritchard, J. B.

Journal:

AJP Regulatory Integrative and Comparative Physiology

Year:

2006

File:

PDF, 9 KB

2006

48

Utility of unbound plasma drug levels and P-glycoprotein transport data in prediction of central nervous system exposure

He, H., Lyons, K.A., Shen, X., Yao, Z., Bleasby, K., Chan, G., Hafey, M., Li, X., Xu, S., Salituro, G. M., Cohen, L. H., Tang, W.

Journal:

Year:

2009

Language:

english

File:

PDF, 714 KB

english, 2009

49

SERPENT—an information storage and analysis resource for protein sequences

D. Akrigg, T. Attwood, A. Bleasby, J. Findlay, A. North, N. Maughan, D. Parry-smith, D. Perkins, J. Wootton

Year:

1992

Language:

english

File:

PDF, 122 KB

english, 1992

50

Letters to the Editor

Bleasby, George, Link, Frederick, Winslow, Donald J., Lovett, Francis W.

Journal:

College English

Year:

1956

Language:

english

File:

PDF, 223 KB

english, 1956